A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Singhal, Parul
- Breast Hamartoma - an Underdiagnosed Entity
Authors
1 Deptt. of Pathology, Saraswathi Medical College, Hapur
2 Deptt of Pathology, Santosh Medical College, Ghaziabad
Source
Indian Journal of Public Health Research & Development, Vol 4, No 2 (2013), Pagination: 232-233Abstract
Hamartomas or fibroadenolipomas are benign breast lesions often misdiagnosed as Fibroadenomas on clinical examination and after fine needle aspiration cytology. The relevant investigation in these cases has come out to be radiological assessment, especially mammography. The following case shows how the histopathological and clinical correlation achieved the diagnosis of hamartoma and prevented its misdiagnosis as Fibroadenoma.Keywords
Hamartoma, Mammography, Fibroadenoma
References
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- Comparative Cytomorphological Profile of Paediatric and Adult Lymphadenopathy with Emphasis on Smear Characteristics in Tuberculous Lymphadenitis
Authors
1 Pathology Department, Santosh Medical College, Ghaziabad, IN
2 Division of Cytopathology, Institute of Cytology & Preventive Oncology (ICMR), New Delhi, IN
Source
Indian Journal of Public Health Research & Development, Vol 3, No 2 (2012), Pagination: 127-130Abstract
Aims
1. To compare the cytological spectrum of pediatric and adult lymphadenopathy.
2. To analyze the differences between and cytomorphological appearances of the aspirates from tuberculous lymph nodes in the two age groups.
Material and Methods
Fine needle aspirate (FNA) smears from 500 consecutive patients with peripheral lymphadenopathy, each in paediatric (≤ 14 years) and adult (> 14 years) age groups, were retrospectively analyzed. Smear patterns in tuberculous lymphadenitis were studied in detail. The smears were air dried and stained by May Grunwald Giemsa (MGG) stain. Ziehl Neilson (ZN) staining to demonstrate acid fast bacilli (AFB) was performed where necessary.
Observations
The most frequent diagnosis on FNA was tuberculosis in both age groups (children 57%, adults 82 %), followed by reactive hyperplasia in children (37.8 %) and metastasis in adults (7.9%). Frequency of tuberculosis was significantly more in adults (p <0.001) while that of reactive process was significantly more in children (p<0.001). Cervical lymph nodes were involved most frequently by tubercular process (children 87%, adults 84 %). Caseous material or pus was aspirated in almost 2/3rd patients. The most frequent microscopic pattern was presence of granulomas against a lymphoid background, followed by necrosis only and the highest AFB positivity was found in necrotic smears in both age groups. Acute/ mixed inflammatory response, devoid of granulomas, was observed significantly more often in children as compared to adults. (p< 0.001).
Conclusions
FNAC is a useful, minimally invasive first line investigation to evaluate lymphadenopathy. An early diagnosis on FNA allows clinicians to plan and institute appropriate treatment in most cases.
Keywords
Lymph Node, Fine Needle Aspiration Cytology, Tuberculous LymphadenititsReferences
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